Lean gene 'linked to heart risk'

Genes that result in a slender figure have been linked to heart disease and type-two diabetes, conditions normally associated with being overweight. A study suggests variants of the IRS1 gene reduce fat under the skin, but not the more dangerous visceral fat around organs such as the heart and liver. The Medical Research Council study, published in Nature Genetics, examined the genes of more than 76,000 people. The link between the genetic variants and the conditions was stronger in men