...custome lothsome to the eye, hatefull to the Nose, harmefull to the braine, daungerous to the Lungs, and in the blacke stinking fume thereof, neerest resembling the horrible Stigian smoke of the pit that is bottomlesse.
Comparing smoking to the smoky fires of hell is pretty strong stuff, but, as the BMJ's Wendy Moore points out, his advice would go unheeded for centuries"
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