Ontario's first cardiac stem cell transplant performed at the Peter Munk Cardiac Centre (Canada)

Heart failure is a leading cause of death in Canada. As part of the ongoing IMPACT-CABG clinical trial to treat advanced heart failure, physicians at the Peter Munk Cardiac Centre performed the first cardiac stem cell transplant in Ontario using stem cells derived from the patient's own bone marrow, isolated completely within the operating room, and implanted into the heart at the time of coronary bypass surgery. Researchers hope that stem cell therapy may be developed into a novel treatment for the 50,000 Canadians diagnosed each year with advanced heart failure. The first patient to receive this type of stem cell therapy, James Culross, a 67-year-old man from Etobicoke, will be discharged this week after 2.83 million stem cells were injected into seven sites where his heart had been damaged by a heart attack in November 2011. The stem cells were injected following coronary artery bypass graft (CABG) surgery, by a multi-disciplinary team led by Dr. Terrence Yau, Cardiac Surgeon and Director of the Cardiac Stem Cell Therapy Program at the Peter Munk Cardiac Centre. A second patient underwent successful stem cell implantation and CABG surgery at the Peter Munk Cardiac Centre