Wednesday, December 10, 2008

Modified protein heart attack hope

"Modifying a natural protein found in narrowed arteries could help prevent heart attacks and strokes, new research suggests. The protein, N-cadherin, helps cells stick together and build up scaly deposits on artery walls. These 'plaques' are then liable to rupture, with dangerous consequences. A thicker blockage can result when the rupture site seals over, and the fatty particles released may become lodged in blood vessels, leading to heart attacks or strokes. Scientists in Bristol have now produced a smaller, soluble form of N-cadherin that has the ability to stabilise plaques, making them less likely to rupture. The research, funded by the British Heart Foundation, is reported in the journal Arteriosclerosis, Thrombosis And Vascular Biology" - MSN

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